The predictive value of precise-dapt score for mortality in patients with acute decompansed heart failure

• Main Authors: Mevlut Demir, Ahmet Korkmaz, Bekir Demirtas
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2021-01-01
• Series: International Journal of the Cardiovascular Academy
• Subjects: heart failure; mortality; score
• Online Access: http://www.ijcva.com/article.asp?issn=2405-8181;year=2021;volume=7;issue=3;spage=70;epage=77;aulast=Demir
• ISSN: 2405-8181; 2405-819X

Introduction: Acute decompensated heart failure (ADHF) is an emergency clinical syndrome defined as a sudden worsening of heart failure. PREdicting bleeding Complications In patients undergoing Stent implantation and subsEquent Dual Anti-Platelet Therapy (PRECISE-DAPT) score is a new scoring used in the management of duration of dual-antiplatelet therapy after coronary intervention. We presented the hypothesis that this scoring can be used as a predictor of mortality in heart failure. Objective: In this study, the correlation between mortality and PRECISE-DAPT score will be analyzed in patients diagnosed with ADHF. Materials and Methods: A total of 114 patients hospitalized with a diagnosis of ADHF were included in this study. The patients were divided into two groups: PRECISE-DAPT score ≥25 and PRECISE-DAPT score <25, and these groups were evaluated in terms of correlation with early (<6 months), late (>6 months) and overall mortality. Results: According to univariate analysis, it was found that PRECISE-DAPT score was significantly related with early (P < 0.001), late (P < 0.001), and overall (P < 0.001) mortality. Multivariate Cox regression analysis showed that PRECISE-DAPT was independently associated with late (hazard ratio: 6.6; 95% confidence interval [CI] 1.6–27.3; P = 0.009) and overall (hazard ratio: 11.3; 95% CI 3.2–40.9; P < 0.001) mortality. According to Kaplan–Meier curve, those with a score of ≥25 were shown to have significantly higher mortality. The predictive ability for the PRECISE-DAPT score threshold value of 25 was investigated in 3 mortality subgroups. Conclusion: The PRECISE-DAPT score may be a significant independent predictor of mortality in patients with ADHF. Limitations: This study is subject to the limitations inherent to a retrospective study and the sample size in our study is relatively small.