Genomewide binding of transcription factor Snail1 in triple‐negative breast cancer cells

Genomewide binding of transcription factor Snail1 in triple‐negative breast cancer cells

Transcriptional regulation mediated by the zinc finger protein Snail1 controls early embryogenesis. By binding to the epithelial tumor suppressor CDH1 gene, Snail1 initiates the epithelial–mesenchymal transition (EMT). The EMT generates stem‐like cells and promotes invasiveness during cancer progres...

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Bibliographic Details
Main Authors: Varun Maturi, Anita Morén, Stefan Enroth, Carl‐Henrik Heldin, Aristidis Moustakas
Format: Article
Language:English
Published: Wiley 2018-06-01
Series:Molecular Oncology
Subjects:
bone morphogenetic protein
breast cancer
chromatin immunoprecipitation
epithelial–mesenchymal transition
transforming growth factor β
Online Access:https://doi.org/10.1002/1878-0261.12317

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