Neurotrophin-3 regulates ribbon synapse density in the cochlea and induces synapse regeneration after acoustic trauma

Neurotrophin-3 regulates ribbon synapse density in the cochlea and induces synapse regeneration after acoustic trauma

Neurotrophin-3 (Ntf3) and brain derived neurotrophic factor (Bdnf) are critical for sensory neuron survival and establishment of neuronal projections to sensory epithelia in the embryonic inner ear, but their postnatal functions remain poorly understood. Using cell-specific inducible gene recombinat...

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Bibliographic Details
Main Authors: Guoqiang Wan, Maria E Gómez-Casati, Angelica R Gigliello, M Charles Liberman, Gabriel Corfas
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-10-01
Series:eLife
Subjects:
deafness
synaptogenesi
hearing loss
neuron-glia interaction
glial cell
Online Access:https://elifesciences.org/articles/03564

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