A SAS Package for Logistic Two-Phase Studies

Two-phase designs, in which for a large study a dichotomous outcome and partial or proxy information on risk factors is available, whereas precise or complete measurements on covariates have been obtained only in a stratified sub-sample, extend the standard case-control design and have been proven u...

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Main Authors: Walter Schill, Dirk Enders, Karsten Drescher
Format: Article
Language:English
Published: Foundation for Open Access Statistics 2014-04-01
Series:Journal of Statistical Software
Online Access:http://www.jstatsoft.org/index.php/jss/article/view/2136
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spelling doaj-95823b86c3094ad89310a0b45de802b52020-11-24T23:47:14ZengFoundation for Open Access StatisticsJournal of Statistical Software1548-76602014-04-0157111310.18637/jss.v057.i09740A SAS Package for Logistic Two-Phase StudiesWalter SchillDirk EndersKarsten DrescherTwo-phase designs, in which for a large study a dichotomous outcome and partial or proxy information on risk factors is available, whereas precise or complete measurements on covariates have been obtained only in a stratified sub-sample, extend the standard case-control design and have been proven useful in practice. The application of two-phase designs, however, seems to be hampered by the lack of appropriate, easy-to-use software. This paper introduces sas-twophase-package, a collection of SAS-macros, to fulfill this task. sas-twophase-package implements weighted likelihood, pseudo likelihood and semi- parametric maximum likelihood estimation via the EM algorithm and via profile likelihood in two-phase settings with dichotomous outcome and a given stratification.http://www.jstatsoft.org/index.php/jss/article/view/2136
collection DOAJ
language English
format Article
sources DOAJ
author Walter Schill
Dirk Enders
Karsten Drescher
spellingShingle Walter Schill
Dirk Enders
Karsten Drescher
A SAS Package for Logistic Two-Phase Studies
Journal of Statistical Software
author_facet Walter Schill
Dirk Enders
Karsten Drescher
author_sort Walter Schill
title A SAS Package for Logistic Two-Phase Studies
title_short A SAS Package for Logistic Two-Phase Studies
title_full A SAS Package for Logistic Two-Phase Studies
title_fullStr A SAS Package for Logistic Two-Phase Studies
title_full_unstemmed A SAS Package for Logistic Two-Phase Studies
title_sort sas package for logistic two-phase studies
publisher Foundation for Open Access Statistics
series Journal of Statistical Software
issn 1548-7660
publishDate 2014-04-01
description Two-phase designs, in which for a large study a dichotomous outcome and partial or proxy information on risk factors is available, whereas precise or complete measurements on covariates have been obtained only in a stratified sub-sample, extend the standard case-control design and have been proven useful in practice. The application of two-phase designs, however, seems to be hampered by the lack of appropriate, easy-to-use software. This paper introduces sas-twophase-package, a collection of SAS-macros, to fulfill this task. sas-twophase-package implements weighted likelihood, pseudo likelihood and semi- parametric maximum likelihood estimation via the EM algorithm and via profile likelihood in two-phase settings with dichotomous outcome and a given stratification.
url http://www.jstatsoft.org/index.php/jss/article/view/2136
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