| Summary: | Among the innovations that have changed modern orthodontics, the introduction of new digital technologies in daily clinical practice has had a major impact, in particular the use of 3D models of dental arches. The possibility for direct 3D capture of arches using intraoral scanners has brought many clinicians closer to the digital world. The digital revolution of orthodontic practice requires both hardware components and dedicated software for the analysis of STL models and all other files generated by the digital workflow. However, there are some negative aspects, including the need for the clinician and technicians to learn how to use new software. In this context, we can distinguish two main software types: dedicated software (i.e., developed by orthodontic companies) and open-source software. Dedicated software tend to have a much more user-friendly interface, and be easier to use and more intuitive, due to being designed and developed for a non-expert user, but very high rental or purchase costs are an issue. Therefore, younger clinicians with more extensive digital skills have begun to look with increasing interest at open-source software. The aim of the present study was to present and discuss some of the best-known open-source software for analysis of 3D models and the creation of orthodontic devices: Blue Sky Plan, MeshMixer, ViewBox, and Blender.
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