Isolation and characterization of malaria PfHRP2 specific VNAR antibody fragments from immunized shark phage display library
Abstract Background Malaria rapid diagnostic tests (RDTs) represent an important antibody based immunoassay platform. Unfortunately, conventional monoclonal antibodies are subject to degradation shortening shelf lives of RDTs. The variable region of the receptor (VNAR) from shark has a potential as...
Main Authors: | Chiuan Herng Leow, Katja Fischer, Chiuan Yee Leow, Katleen Braet, Qin Cheng, James McCarthy |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-10-01
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Series: | Malaria Journal |
Online Access: | http://link.springer.com/article/10.1186/s12936-018-2531-y |
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