Anti-pseudomonad Activity of Manuka Honey and Antibiotics in a Specialized ex vivo Model Simulating Cystic Fibrosis Lung Infection

Anti-pseudomonad Activity of Manuka Honey and Antibiotics in a Specialized ex vivo Model Simulating Cystic Fibrosis Lung Infection

Pseudomonas aeruginosa causes problematic chronic lung infections in those suffering from cystic fibrosis. This is due to its antimicrobial resistance mechanisms and its ability to form robust biofilm communities with increased antimicrobial tolerances. Using novel antimicrobials or repurposing curr...

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Bibliographic Details
Main Authors: Aled E. L. Roberts, Lydia C. Powell, Manon F. Pritchard, David W. Thomas, Rowena E. Jenkins
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Microbiology
Subjects:
Pseudomonas aeruginosa
biofilms
antimicrobial susceptibility testing
manuka honey
ex vivo model
cystic fibrosis
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00869/full

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