Human-stimulated oocyte extract induces genetic and mitochondrial reprogramming of mesenchymal stromal cells.

SUMMARY:Reprogramming autologous adult cells to pluripotent cells allows for relatively safe cell replacement therapy. This can be achieved by nuclear transfer, cell fusion, or induced pluripotent stem cell technology However, the epigenetic memory of the cell is considered as a great challenge faci...

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Bibliographic Details
Main Authors: Zaynab El-Gammal, Abdelrahman AlOkda, Sameh S Ali, Asmaa Reda, Sameh Magdeldin, Ragaa Mansour, Nagwa El-Badri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0232759