Sphingosine-1-phosphate in Endothelial Cell Recellularization Improves Patency and Endothelialization of Decellularized Vascular Grafts In Vivo

Sphingosine-1-phosphate in Endothelial Cell Recellularization Improves Patency and Endothelialization of Decellularized Vascular Grafts In Vivo

Background: S1P has been shown to improve the endothelialization of decellularized vascular grafts in vitro. Here, we evaluated the potential of tissue-engineered vascular grafts (TEVGs) constructed by ECs and S1P on decellularized vascular scaffolds in a rat model. Methods: Rat aorta was decellular...

Full description

Bibliographic Details
Main Authors: Kai Hsia, Chih-Hsun Lin, Hsin-Yu Lee, Wei-Min Chen, Chao-Ling Yao, Chien-Chin Chen, Hsu Ma, Shyh-Jen Wang, Jen-Her Lu
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
sphingosine-1-phosphate
vascular graft
endothelial cell
thrombosis
syndecan-1
Online Access:https://www.mdpi.com/1422-0067/20/7/1641

Similar Items

Similar Items