Human Islet Response to Selected Type 1 Diabetes-Associated Bacteria: A Transcriptome-Based Study

Human Islet Response to Selected Type 1 Diabetes-Associated Bacteria: A Transcriptome-Based Study

Type 1 diabetes (T1D) is a chronic autoimmune disease that results from destruction of pancreatic β-cells. T1D subjects were recently shown to harbor distinct intestinal microbiome profiles. Based on these findings, the role of gut bacteria in T1D is being intensively investigated. The mechanism con...

Full description

Bibliographic Details
Main Authors:	Ahmed M. Abdellatif, Heather Jensen Smith, Robert Z. Harms, Nora E. Sarvetnick
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-11-01
Series:	Frontiers in Immunology
Subjects:	autoimmunity Bacteroides dorei β-cell dysbiosis Ruminococcus gnavus type 1 diabetes
Online Access:	https://www.frontiersin.org/article/10.3389/fimmu.2019.02623/full

Similar Items

Genetic diversity of <FONT FACE=Symbol>b</font>-glucuronidase activity among 14 strains of the dominant human gut anaerobe Ruminococcus gnavus
by: Diane Beaud, et al.
Published: (2006-01-01)

Adalimumab Therapy Improves Intestinal Dysbiosis in Crohn’s Disease
by: Davide Giuseppe Ribaldone, et al.
Published: (2019-10-01)

Bacteroides dorei dominates gut microbiome prior to autoimmunity in Finnish children at high risk for type 1 diabetes.
by: Austin G Davis-Richardson, et al.
Published: (2014-12-01)

Investigating the structure, function and regulation of Ruminococcus gnavus E1 [alpha]-galactosidases
by: Cervera -Tison, Marine
Published: (2011)

Toward Understanding Phage:Host Interactions in the Rumen; Complete Genome Sequences of Lytic Phages Infecting Rumen Bacteria
by: Rosalind A. Gilbert, et al.
Published: (2017-12-01)

Caractérisation d'un nouveau RiPP issu du microbiote intestinal : la Ruminococcin C
by: Balty, Clémence
Published: (2019)

The association between gut microbiota development and maturation of intestinal bile acid metabolism in the first 3 y of healthy Japanese infants
by: Masaru Tanaka, et al.
Published: (2020-03-01)

Development of a novel human intestinal model to elucidate the effect of anaerobic commensals on Escherichia coli infection
by: Bell, A., et al.
Published: (2022)

TH1 cell-inducing Escherichia coli strain identified from the small intestinal mucosa of patients with Crohn’s disease
by: Manabu Nagayama, et al.
Published: (2020-11-01)

The Multifunctional Sactipeptide Ruminococcin C1 Displays Potent Antibacterial Activity In Vivo as Well as Other Beneficial Properties for Human Health
by: Clarisse Roblin, et al.
Published: (2021-03-01)

Les bactériocines RumC, une nouvelle famille de peptides antimicrobiens comme alternative aux antibiotiques conventionnels
by: Chiumento, Steve
Published: (2019)

First case of an invasive Bacteroides dorei infection detected in a patient with a mycotic aortic aneurysm—raising a rebellion of major indigenous bacteria in humans: a case report and review
by: Takayuki Matsuoka, et al.
Published: (2021-06-01)

Diet, Microbiota and Immune System in Type 1 Diabetes Development and Evolution
by: María E. Mejía-León, et al.
Published: (2015-11-01)

Gut Microbiota Dysbiosis Accelerates Prostate Cancer Progression Through Increased LPCAT1 Expression and Enhanced DNA Repair Pathways
by: Yufei Liu, et al.
Published: (2021-06-01)

Insights from <i>Bacteroides</i> Species in Children with Type 1 Diabetes
by: José Matos, et al.
Published: (2021-07-01)

Rumen microbial community and nitrogen metabolism in goats fed blend of palm oil and canola oil
by: Kazeem Dauda Adeyemi, et al.
Published: (2016-10-01)

Abnormal T Cell Frequencies, Including Cytomegalovirus-Associated Expansions, Distinguish Seroconverted Subjects at Risk for Type 1 Diabetes
by: Robert Z. Harms, et al.
Published: (2018-10-01)

Anti-human Interleukin(IL)-4 Clone 8D4-8 Cross-Reacts With Myosin-9 Associated With Apoptotic Cells and Should Not Be Used for Flow Cytometry Applications Querying IL-4 Expression
by: Robert Z. Harms, et al.
Published: (2019-04-01)

Effects of dietary supplementation of leaves and whole plant of Andrographis paniculata on rumen fermentation, fatty acid composition and microbiota in goats
by: Aisha L. Yusuf, et al.
Published: (2017-11-01)

Coordinated Induction of Antimicrobial Response Factors in Systemic Lupus Erythematosus
by: Prathapan Ayyappan, et al.
Published: (2019-04-01)

Interaction of Intestinal Bacteria with Human Rotavirus during Infection in Children
by: Roberto Gozalbo-Rovira, et al.
Published: (2021-01-01)

A Previously Undescribed Highly Prevalent Phage Identified in a Danish Enteric Virome Catalog
by: Arumugam, M., et al.
Published: (2021)

Polyethylene glycol and polyvinylpirrolidone effect on bacterial rRNA extraction and hybridization from cells exposed to tannins Efeito de polietilenoglicol e polivinilpirrolidona na extração e hibridização de rRNA bacteriano de células expostas a taninos
by: Pedro Braga Arcuri, et al.
Published: (2003-09-01)

Decrease in abundance of bacteria of the genus Bifidobacterium in gut microbiota may be related to pre-eclampsia progression in women from East China
by: Tingting Miao, et al.
Published: (2021-06-01)

Confirmation and Identification of Biomarkers Implicating Environmental Triggers in the Pathogenesis of Type 1 Diabetes
by: Robert Z. Harms, et al.
Published: (2020-09-01)

Infant early gut colonization by Lachnospiraceae: high frequency of Ruminococcus gnavus
by: Valeria eSagheddu, et al.
Published: (2016-06-01)

Bacteroides ovatus ATCC 8483 monotherapy is superior to traditional fecal transplant and multi-strain bacteriotherapy in a murine colitis model
by: Faith D. Ihekweazu, et al.
Published: (2019-07-01)

Temporal changes in gut microbiota profile in children with acute lymphoblastic leukemia prior to commencement-, during-, and post-cessation of chemotherapy
by: Ling Ling Chua, et al.
Published: (2020-02-01)

Potential of Selected Rumen Bacteria for Cellulose and Hemicellulose Degradation
by: Maša Zorec, et al.
Published: (2014-01-01)

Interleukin (IL)-18 Binding Protein Deficiency Disrupts Natural Killer Cell Maturation and Diminishes Circulating IL-18
by: Robert Z. Harms, et al.
Published: (2017-08-01)

Dynamics of Human Gut Microbiota and Short-Chain Fatty Acids in Response to Dietary Interventions with Three Fermentable Fibers
by: Nielson T. Baxter, et al.
Published: (2019-01-01)

Impact of Dietary or Drinking Water Ruminococcus sp. Supplementation and/or Heat Stress on Growth, Histopathology, and Bursal Gene Expression of Broilers
by: Adel Hassan Saad, et al.
Published: (2021-06-01)

Estudos estruturais de dockerinas e cohesinas em Ruminococcus flavefaciens e sua aplicação no desenvolvimento de matrizes auto montáveis de proteínas
by: Gabriel Belem de Andrade
Published: (2017)

Estudos estruturais de dockerinas e cohesinas em Ruminococcus flavefaciens e sua aplicação no desenvolvimento de matrizes auto montáveis de proteínas
by: Andrade, Gabriel Belem de
Published: (2017)

Characterization of Bacteroides melaninogenicus and its role in mixed anaerobic infections
by: Mayrand, Denis
Published: (2010)

Antibiotics and the human gut microbiome: dysbioses and accumulation of resistances
by: M Pilar eFrancino
Published: (2016-01-01)

Ketamine interactions with gut-microbiota in rats: relevance to its antidepressant and anti-inflammatory properties
by: Bruk Getachew, et al.
Published: (2018-12-01)

Enterotoxigenic and nontoxigenic Bacteroides fragilis strains isolated in Brazil
by: Karla R Miranda, et al.
Published: (2008-11-01)

The Microbiota Profile in Inflamed and Non-Inflamed Ileal Pouch–Anal Anastomosis
by: Sabrina Just Kousgaard, et al.
Published: (2020-10-01)

Bacteroides fragilis Protects Against Antibiotic-Associated Diarrhea in Rats by Modulating Intestinal Defenses
by: Wendi Zhang, et al.
Published: (2018-05-01)