Stress-induced TRBP phosphorylation enhances its interaction with PKR to regulate cellular survival

Abstract Transactivation response element RNA-binding protein (TRBP or TARBP2) initially identified to play an important role in human immunodeficiency virus (HIV) replication also has emerged as a regulator of microRNA biogenesis. In addition, TRBP functions in signaling pathways by negatively regu...

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Bibliographic Details
Main Authors: Evelyn Chukwurah, Rekha C. Patel
Format: Article
Language:English
Published: Nature Publishing Group 2018-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-19360-8