The Role of Tumor Necrosis Factor-α and Interferon-γ in Regulating Angiomotin-Like Protein 1 Expression in Lung Microvascular Endothelial Cells

Background: Angiogenesis in the alveolar septa is thought be a critical factor in pulmonary emphysema. Angiomotin-like protein 1 (AmotL1) is involved in angiogenesis via regulating endothelial cell function. However, the role of AmotL1 in the pathogenesis of pulmonary emphysema has not been elucidat...

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Bibliographic Details
Main Authors: Yoshio Nakajima, Yutaka Nakamura, Wataru Shigeeda, Makoto Tomoyasu, Hiroyuki Deguchi, Tatsuo Tanita, Kohei Yamauchi
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Allergology International
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Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015301441