Recent Developments in the Reduction of Oxidative Stress through Antioxidant Polymeric Formulations

Reactive oxygen and nitrogen species (RONS) are produced endogenously in our body, or introduced through external factors, such as pollution, cigarette smoke, and excessive sunlight exposure. In normal conditions, there is a physiological balance between pro-oxidant species and antioxidant molecules...

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Main Authors:	Muhammad Shajih Zafar, Alessandra Quarta, Marco Marradi, Andrea Ragusa
Format:	Article
Language:	English
Published:	MDPI AG 2019-10-01
Series:	Pharmaceutics
Subjects:	antioxidant radicals ros polymer chitosan extract film hydrogel nanoparticle
Online Access:	https://www.mdpi.com/1999-4923/11/10/505

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spelling	doaj-9538f2655a7b4cf78fc479700da3d90f2020-11-25T01:18:38ZengMDPI AGPharmaceutics1999-49232019-10-01111050510.3390/pharmaceutics11100505pharmaceutics11100505Recent Developments in the Reduction of Oxidative Stress through Antioxidant Polymeric FormulationsMuhammad Shajih Zafar0Alessandra Quarta1Marco Marradi2Andrea Ragusa3Department of Engineering for Innovation, University of Salento, via Monteroni, 73100 Lecce, ItalyCNR Nanotec, Institute of Nanotechnology, via Monteroni, 73100 Lecce, ItalyDepartment of Chemistry “Ugo Schiff”, University of Florence, via della Lastruccia 13, Sesto Fiorentino, 50019 Firenze, ItalyDepartment of Engineering for Innovation, University of Salento, via Monteroni, 73100 Lecce, ItalyReactive oxygen and nitrogen species (RONS) are produced endogenously in our body, or introduced through external factors, such as pollution, cigarette smoke, and excessive sunlight exposure. In normal conditions, there is a physiological balance between pro-oxidant species and antioxidant molecules that are able to counteract the detrimental effect of the former. Nevertheless, when this homeostasis is disrupted, the resulting oxidative stress can lead to several pathological conditions, from inflammation to cancer and neurodegenerative diseases. In this review, we report on the recent developments of different polymeric formulations that are able to reduce the oxidative stress, from natural extracts, to films and hydrogels, and finally to nanoparticles (NPs).https://www.mdpi.com/1999-4923/11/10/505antioxidantradicalsrospolymerchitosanextractfilmhydrogelnanoparticle
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Muhammad Shajih Zafar Alessandra Quarta Marco Marradi Andrea Ragusa
spellingShingle	Muhammad Shajih Zafar Alessandra Quarta Marco Marradi Andrea Ragusa Recent Developments in the Reduction of Oxidative Stress through Antioxidant Polymeric Formulations Pharmaceutics antioxidant radicals ros polymer chitosan extract film hydrogel nanoparticle
author_facet	Muhammad Shajih Zafar Alessandra Quarta Marco Marradi Andrea Ragusa
author_sort	Muhammad Shajih Zafar
title	Recent Developments in the Reduction of Oxidative Stress through Antioxidant Polymeric Formulations
title_short	Recent Developments in the Reduction of Oxidative Stress through Antioxidant Polymeric Formulations
title_full	Recent Developments in the Reduction of Oxidative Stress through Antioxidant Polymeric Formulations
title_fullStr	Recent Developments in the Reduction of Oxidative Stress through Antioxidant Polymeric Formulations
title_full_unstemmed	Recent Developments in the Reduction of Oxidative Stress through Antioxidant Polymeric Formulations
title_sort	recent developments in the reduction of oxidative stress through antioxidant polymeric formulations
publisher	MDPI AG
series	Pharmaceutics
issn	1999-4923
publishDate	2019-10-01
description	Reactive oxygen and nitrogen species (RONS) are produced endogenously in our body, or introduced through external factors, such as pollution, cigarette smoke, and excessive sunlight exposure. In normal conditions, there is a physiological balance between pro-oxidant species and antioxidant molecules that are able to counteract the detrimental effect of the former. Nevertheless, when this homeostasis is disrupted, the resulting oxidative stress can lead to several pathological conditions, from inflammation to cancer and neurodegenerative diseases. In this review, we report on the recent developments of different polymeric formulations that are able to reduce the oxidative stress, from natural extracts, to films and hydrogels, and finally to nanoparticles (NPs).
topic	antioxidant radicals ros polymer chitosan extract film hydrogel nanoparticle
url	https://www.mdpi.com/1999-4923/11/10/505
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Recent Developments in the Reduction of Oxidative Stress through Antioxidant Polymeric Formulations

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