Development and characterization of liposomal formulation of bortezomib

Bortezomib is a proteasome inhibitor used for the treatment of multiple myeloma. The poor pharmacokinetic profile and off-target adverse effects provide a strong incentive to develop drug delivery systems for bortezomib. In the past, liposomal encapsulation has been proven to improve the therapeutic...

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Bibliographic Details
Main Authors: Anil K. Deshantri, Josbert M. Metselaar, Stavroula Zagkou, Gert Storm, Sanjay N. Mandhane, Marcel H.A.M. Fens, Raymond M. Schiffelers
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:International Journal of Pharmaceutics: X
Online Access:http://www.sciencedirect.com/science/article/pii/S2590156719300258