Iron Deficiency Reprograms Phosphorylation Signaling and Reduces O-GlcNAc Pathways in Neuronal Cells

Iron Deficiency Reprograms Phosphorylation Signaling and Reduces O-GlcNAc Pathways in Neuronal Cells

Micronutrient sensing is critical for cellular growth and differentiation. Deficiencies in essential nutrients such as iron strongly affect neuronal cell development and may lead to defects in neuronal function that cannot be remedied by subsequent iron supplementation. To understand the adaptive in...

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Bibliographic Details
Main Authors: Luke N. Erber, Ang Luo, Yao Gong, Montana Beeson, Maolin Tu, Phu Tran, Yue Chen
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Nutrients
Subjects:
oxygen sensing
hypoxia
iron deficiency
quantitative proteomics
phosphorylation
neuronal cells
Online Access:https://www.mdpi.com/2072-6643/13/1/179

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