Genotype-specific acquisition, evolution and adaptation of characteristic mutations in hepatitis E virus
Hepatitis E virus (HEV) infection is a major cause of acute hepatitis but also provokes chronic infection in immunocompromised patients. Although the pathogenesis and treatment outcome involve complex interplay between the virus and host, the nature of adaptive responses of HEV to the host immune sy...
Main Authors: | Aqsa Ikram, Mohamad S. Hakim, Jian-hua Zhou, Wenshi Wang, Maikel P. Peppelenbosch, Qiuwei Pan |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2018-12-01
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Series: | Virulence |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/21505594.2017.1358349 |
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