Leukemia Inhibitory Factor Enhances Endogenous Cardiomyocyte Regeneration after Myocardial Infarction.

Cardiac stem cells or precursor cells regenerate cardiomyocytes; however, the mechanism underlying this effect remains unclear. We generated CreLacZ mice in which more than 99.9% of the cardiomyocytes in the left ventricular field were positive for 5-bromo-4-chloro-3-indolyl-β-d-galactoside (X-gal)...

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Main Authors: Masato Kanda, Toshio Nagai, Toshinao Takahashi, Mei Lan Liu, Naomichi Kondou, Atsuhiko T Naito, Hiroshi Akazawa, Goro Sashida, Atsushi Iwama, Issei Komuro, Yoshio Kobayashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4881916?pdf=render