Translational regulation of GPx-1 and GPx-4 by the mTOR pathway.

Glutathione peroxidase activity was previously determined to be elevated in lymphocytes obtained from patients treated with the Bcr-Abl kinase inhibitor imatinib mesylate. In order to expand upon this observation, the established chronic myelogenous leukemia cell lines KU812 and MEG-01 were treated...

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Bibliographic Details
Main Authors: Emily N Reinke, Dede N Ekoue, Soumen Bera, Nadim Mahmud, Alan M Diamond
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3972146?pdf=render