Perivascular macrophages create an intravascular niche for CD8+ T cell localisation prior to the onset of fatal experimental cerebral malaria

Perivascular macrophages create an intravascular niche for CD8+ T cell localisation prior to the onset of fatal experimental cerebral malaria

Abstract Objectives The immunologic events that build up to the fatal neurological stage of experimental cerebral malaria (ECM) are incompletely understood. Here, we dissect immune cell behaviour occurring in the central nervous system (CNS) when Plasmodium berghei ANKA (PbA)‐infected mice show only...

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Bibliographic Details
Main Authors: Jim Qin, Michael D Lovelace, Andrew J Mitchell, Tania deKoning‐Ward, Georges ER Grau, Saparna Pai
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Clinical & Translational Immunology
Subjects:
CD8+ T cells
perivascular macrophage
malaria
immune response
2‐photon intravital microscopy
Online Access:https://doi.org/10.1002/cti2.1273

Internet

https://doi.org/10.1002/cti2.1273

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