Serum Lipid Profile of Newly Diagnosed Hypertensive Patients in Nnewi, South-East Nigeria

Abnormalities in serum lipid and lipoprotein levels are recognized major modifiable cardiovascular disease and essential hypertension risk factors. The objective of this study was to examine the serum lipid patterns of newly diagnosed hypertensive patients attending a tertiary healthcare centre in S...

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Main Authors: Charles U. Osuji, Emeka G. Omejua, Emmanuel I. Onwubuya, Gladys I. Ahaneku
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:International Journal of Hypertension
Online Access:http://dx.doi.org/10.1155/2012/710486
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spelling doaj-95071560362a49f7a019c30b483a2b0c2020-11-24T22:26:22ZengHindawi LimitedInternational Journal of Hypertension2090-03842090-03922012-01-01201210.1155/2012/710486710486Serum Lipid Profile of Newly Diagnosed Hypertensive Patients in Nnewi, South-East NigeriaCharles U. Osuji0Emeka G. Omejua1Emmanuel I. Onwubuya2Gladys I. Ahaneku3Department of Medicine, Nnamdi Azikiwe University Teaching Hospital, PMB 5025, Nnewi 435101, Anambra State, NigeriaDepartment of Medicine, Federal Medical Centre, P.O. Box 1010, Owerri 460281, Imo State, NigeriaDepartment of Medicine, Nnamdi Azikiwe University Teaching Hospital, PMB 5025, Nnewi 435101, Anambra State, NigeriaDepartment of Medicine, Nnamdi Azikiwe University Teaching Hospital, PMB 5025, Nnewi 435101, Anambra State, NigeriaAbnormalities in serum lipid and lipoprotein levels are recognized major modifiable cardiovascular disease and essential hypertension risk factors. The objective of this study was to examine the serum lipid patterns of newly diagnosed hypertensive patients attending a tertiary healthcare centre in South East Nigeria. Methods. Two hundred and fifty newly diagnosed adult hypertensive patients and an equal number of age- and sex-matched controls without hypertension were consecutively recruited from the Medical and General Outpatient Clinics of Nnamdi Azikiwe University Teaching Hospital, Nnewi. Result. 126 males and 124 females were in each of the two groups. Mean age was comparable in both groups. Hypertensives had significantly higher mean systolic blood pressure, diastolic blood pressure, body mass index, waist circumference, waist-hip ratio, and fasting blood sugar than the controls. The mean TC, TG, and LDL-C were significantly higher among the hypertensives. The mean HDL-C was comparable; P=0.8. Among the hypertensive subjects, there was statistically significant positive correlation between BMI and TC; LDL-C and TG; WC and TG; FBS and TC; LDL-C and TG. HDL-C showed a statistically significant inverse correlation with WHR in hypertensives. Conclusion. This study showed that lipid abnormalities are highly prevalent among newly diagnosed hypertensives in South-East Nigeria.http://dx.doi.org/10.1155/2012/710486
collection DOAJ
language English
format Article
sources DOAJ
author Charles U. Osuji
Emeka G. Omejua
Emmanuel I. Onwubuya
Gladys I. Ahaneku
spellingShingle Charles U. Osuji
Emeka G. Omejua
Emmanuel I. Onwubuya
Gladys I. Ahaneku
Serum Lipid Profile of Newly Diagnosed Hypertensive Patients in Nnewi, South-East Nigeria
International Journal of Hypertension
author_facet Charles U. Osuji
Emeka G. Omejua
Emmanuel I. Onwubuya
Gladys I. Ahaneku
author_sort Charles U. Osuji
title Serum Lipid Profile of Newly Diagnosed Hypertensive Patients in Nnewi, South-East Nigeria
title_short Serum Lipid Profile of Newly Diagnosed Hypertensive Patients in Nnewi, South-East Nigeria
title_full Serum Lipid Profile of Newly Diagnosed Hypertensive Patients in Nnewi, South-East Nigeria
title_fullStr Serum Lipid Profile of Newly Diagnosed Hypertensive Patients in Nnewi, South-East Nigeria
title_full_unstemmed Serum Lipid Profile of Newly Diagnosed Hypertensive Patients in Nnewi, South-East Nigeria
title_sort serum lipid profile of newly diagnosed hypertensive patients in nnewi, south-east nigeria
publisher Hindawi Limited
series International Journal of Hypertension
issn 2090-0384
2090-0392
publishDate 2012-01-01
description Abnormalities in serum lipid and lipoprotein levels are recognized major modifiable cardiovascular disease and essential hypertension risk factors. The objective of this study was to examine the serum lipid patterns of newly diagnosed hypertensive patients attending a tertiary healthcare centre in South East Nigeria. Methods. Two hundred and fifty newly diagnosed adult hypertensive patients and an equal number of age- and sex-matched controls without hypertension were consecutively recruited from the Medical and General Outpatient Clinics of Nnamdi Azikiwe University Teaching Hospital, Nnewi. Result. 126 males and 124 females were in each of the two groups. Mean age was comparable in both groups. Hypertensives had significantly higher mean systolic blood pressure, diastolic blood pressure, body mass index, waist circumference, waist-hip ratio, and fasting blood sugar than the controls. The mean TC, TG, and LDL-C were significantly higher among the hypertensives. The mean HDL-C was comparable; P=0.8. Among the hypertensive subjects, there was statistically significant positive correlation between BMI and TC; LDL-C and TG; WC and TG; FBS and TC; LDL-C and TG. HDL-C showed a statistically significant inverse correlation with WHR in hypertensives. Conclusion. This study showed that lipid abnormalities are highly prevalent among newly diagnosed hypertensives in South-East Nigeria.
url http://dx.doi.org/10.1155/2012/710486
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