7-Benzyl-3-(4-fluorophenyl)-2-(pyrrolidin-1-yl)-5,6,7,8-tetrahydropyrido[4&#8242;,3&#8242;:4,5]thieno[2,3-d]pyrimidin-4(3H)-one

7-Benzyl-3-(4-fluorophenyl)-2-(pyrrolidin-1-yl)-5,6,7,8-tetrahydropyrido[4&#8242;,3&#8242;:4,5]thieno[2,3-d]pyrimidin-4(3H)-one

In the title compound, C26H25FN4OS, the thienopyrimidine fused-ring system is close to planar (r.m.s. deviation = 0.066&#8197;&#197;), with a maximum deviation of 0.1243&#8197;(17)&#8197;&#197; for the N atom adjacent to the carbonyl group. This ring system fo...

Full description

Bibliographic Details
Main Authors:	Hong Chen, Hai-Jun Hu, Kai Yan, Qiu-Hong Dai
Format:	Article
Language:	English
Published:	International Union of Crystallography 2011-09-01
Series:	Acta Crystallographica Section E
Online Access:	http://scripts.iucr.org/cgi-bin/paper?S1600536811030625

Similar Items

7-Benzyl-3-(4-fluorophenyl)-2-propylamino-5,6,7,8-tetrahydropyrido[4&#8242;,3&#8242;:4,5]thieno[2,3-d]pyrimidin-4(3H)-one
by: Hai-Jun Hu, et al.
Published: (2012-04-01)

7-Benzyl-3-(4-chlorophenyl)-2-isobutylamino-5,6,7,8-tetrahydropyrido[4&#8242;,3&#8242;:4,5]thieno[2,3-d]pyrimidin-4(3H)-one
by: Hong Chen, et al.
Published: (2012-03-01)

7-Benzyl-2-[(cyclopropylmethyl)amino]-3-phenyl-5,6,7,8-tetrahydropyrido[4&#8242;,3&#8242;:4,5]thieno[2,3-d]pyrimidin-4(3H)-one
by: Hong Chen
Published: (2011-08-01)

2-(Dibutylamino)-3-(4-fluorophenyl)-5,6,7,8-tetrahydro-7-methyl-6,8-diphenylpyridine[3′,4′:2,3]thieno[5,4-d]pyrimidin-4(3H)-one
by: Yang-gen Hu, et al.
Published: (2008-02-01)

5-(4-Fluorobenzylidene)-4&#8242;-(4-fluorophenyl)-1,1&#8242;-dimethyldispiro[piperidine-3,3&#8242;-pyrrolidine-2&#8242;,3&#8242;&#8242;-indoline]-4,2&#8242;&#8242;-dione
by: V. Rajni Swamy, et al.
Published: (2012-10-01)

2-Amino-5,7-bis(4-fluorophenyl)-1&#8242;,3&#8242;-dimethyl-7,8-dihydrospiro[pyrido[2,3-d]pyrimidine-6(5H),5&#8242;-pyrimidine]-2&#8242;,4,4&#8242;,6&#8242;(3H,1&#8242;H,3&#8242;H,5&#8242;H)-tetraone ethanol solvate
by: Xiao-Tong Zhu, et al.
Published: (2009-07-01)

3-Phenyl-2-(pyrrolidin-1-yl)-5,6-dihydro-8H-thiopyrano[4&#8242;,3&#8242;:4,5]thieno[2,3-d]pyrimidin-4(3H)-one
by: Shuang-Ming Meng, et al.
Published: (2010-09-01)

Crystal structure of ethyl 2-phenyl-4-(prop-2-yn-1-yloxy)-5,6,7,8-tetrahydropyrido[4′,3′:4,5]thieno[2,3-d]pyrimidine-7-carboxylate
by: Mehmet Akkurt, et al.
Published: (2015-11-01)

4&#8242;-[5-(4-Fluorophenyl)pyridin-3-yl]-1&#8242;-methyldispiro[indan-2,2&#8242;-pyrrolidine-3&#8242;,2&#8242;&#8242;-indan]-1,3,1&#8242;&#8242;-trione
by: Ang Chee Wei, et al.
Published: (2011-09-01)

1&#8242;-Methyl-2-oxo-5&#8242;-phenylspiro[indoline-3,3&#8242;-pyrrolidine]-4&#8242;,4&#8242;-dicarbonitrile
by: Mohammad Reza Nabid, et al.
Published: (2010-01-01)

4&#8242;-(4-Methoxyphenyl)-1,1&#8242;,1&#8242;&#8242;-trimethyldispiro[indoline-3,2&#8242;-pyrrolidine-3&#8242;,3&#8242;&#8242;-pyrrolidine]-2,2&#8242;&#8242;,5&#8242;&#8242;-trione
by: S. Nirmala, et al.
Published: (2009-07-01)

5&#8242;&#8242;-(4-Chlorobenzylidene)-4&#8242;-(4-chlorophenyl)-5-fluoro-1&#8242;,1&#8242;&#8242;-dimethylindoline-3-spiro-2&#8242;-pyrrolidine-3&#8242;-spiro-3&#8242;&#8242;-piperidine-2,4&#8242;&#8242;-dione
by: J. Kalyana Sundar, et al.
Published: (2011-04-01)

2-Dicyclohexylamino-3-phenyl-5,6-dihydro-8H-thiopyrano[4&#8242;,3&#8242;:4,5]thieno[2,3-d]pyrimidin-4(3H)-one
by: Xizhen Liang, et al.
Published: (2011-04-01)

1&#8242;-Benzyl-4,4&#8242;&#8242;-bis(4-chlorophenyl)-3-(2,6-dichlorophenyl)-1&#8242;&#8242;-methyl-4,5-dihydroisoxazole-5-spiro-3&#8242;-piperidine-5&#8242;-spiro-3&#8242;&#8242;-pyrrolidine-2&#8242;&#8242;-spiro-3&#8242;&#8242;&#8242;-indoline-2&#8242;&#8242;&#8242;,4&#8242;-dione
by: Yongjiang Hou
Published: (2010-01-01)

1,1&#8242;-Bis(4-fluorophenyl)-3,3&#8242;-diisobutyl-4,4&#8242;-diphenoxy-1H,1&#8242;H-4,4&#8242;-bipyrazole-5,5&#8242;(4H,4&#8242;H)-dione
by: Hoong-Kun Fun, et al.
Published: (2011-05-01)

6-Benzyl 4-ethyl 2-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-4,6-dicarboxylate
by: Huan-Mei Guo
Published: (2011-09-01)

3&#8242;,7&#8242;,7&#8242;-Trimethyl-1&#8242;-phenyl-5&#8242;,6&#8242;,7&#8242;,8&#8242;-tetrahydrospiro[indoline-3,4&#8242;-(1H,4H-pyrazolo[3,4-b]chromene)]-2,5&#8242;-dione
by: Li-Qin Zhao, et al.
Published: (2010-12-01)

7,7&#8242;,8,8&#8242;-Tetramethoxy-4,4&#8242;-dimethyl-3,3&#8242;-bicoumarin
by: Hoong-Kun Fun, et al.
Published: (2009-06-01)

Ethyl 2-amino-7,7-dimethyl-2&#8242;,5-dioxospiro[5,6,7,8-tetrahydro-4H-chromene-4,3&#8242;(2&#8242;H)-1H-indole]-3-carboxylate
by: Jing Wang, et al.
Published: (2010-02-01)

1,1&#8242;,3,3&#8242;,5,5&#8242;-Hexamethylspiro[furo[2,3-d]pyrimidine-6(5H),5&#8242;-pyrimidine]-2,2&#8242;,4,4&#8242;,6&#8242;(1H,3H,1&#8242;H,3&#8242;H,5&#8242;H)-pentaone
by: Nader Noroozi Pesyan, et al.
Published: (2009-06-01)

Diethyl 1-acetyl-4&#8242;-(4-chlorophenyl)-5&#8242;-(4-nitrophenyl)-2-oxospiro[indoline-3,3&#8242;-pyrrolidine]-2&#8242;,2&#8242;-dicarboxylate
by: Long He
Published: (2009-10-01)

5,6,7,5&#8242;-Tetramethoxy-3&#8242;,4&#8242;-methylenedioxyflavone monohydrate
by: Wen-Jian Lan, et al.
Published: (2012-05-01)

(5&#8242;&#8242;E)-1&#8242;&#8242;-Benzyl-1&#8242;-methyl-5&#8242;&#8242;-[4-(methylsulfanyl)benzylidene]-4&#8242;-[4-(methylsulfanyl)phenyl]dispiro[indoline-3,2&#8242;-pyrrolidine-3&#8242;,3&#8242;&#8242;-piperidine]-2,4&#8242;&#8242;-dione dichloromethane solvate
by: Yongjiang Hou
Published: (2010-01-01)

3&#8242;-(4-Chlorobenzoyl)-4&#8242;-(4-chlorophenyl)-1&#8242;-methylspiro[indoline-3,2&#8242;-pyrrolidin]-2-one
by: T. Srinivasan, et al.
Published: (2011-11-01)

1&#8242;-Methyl-4&#8242;-phenyl-2&#8242;&#8242;-sulfanylidenedispiro[indoline-3,2&#8242;-pyrrolidine-3&#8242;,5&#8242;&#8242;-1,3-thiazolidine]-2,4&#8242;&#8242;-dione
by: Sampath Natarajan, et al.
Published: (2012-02-01)

7&#8242;-Amino-1&#8242;H-spiro[cycloheptane-1,2&#8242;-pyrimido[4,5-d]pyrimidin]-4&#8242;(3&#8242;H)-one
by: Shu Chen, et al.
Published: (2012-08-01)

7,7&#8242;,8,8&#8242;-Tetramethoxy-4,4&#8242;-dimethyl-3,5&#8242;-bichromene-2,2&#8242;-dione
by: Hoong-Kun Fun, et al.
Published: (2009-06-01)

5&#8242;&#8242;-(4-Methoxybenzylidene)-7&#8242;-(4-methoxyphenyl)-1&#8242;&#8242;-methyl-5&#8242;,6&#8242;,7&#8242;,7a'-tetrahydrodispiro[acenaphthene-1,5&#8242;-pyrrolo[1,2-c][1,3]thiazole-6&#8242;,3&#8242;&#8242;-piperidine]-2,4&#8242;&#8242;-dione
by: J. Suresh, et al.
Published: (2011-12-01)

4&#8242;-(2,4-Dichlorophenyl)-1,1&#8242;-dimethylpiperidine-3-spiro-3&#8242;-pyrrolidine-2&#8242;-spiro-3&#8242;&#8242;-indoline-4,2&#8242;&#8242;-dione
by: N. Srinivasan, et al.
Published: (2010-03-01)

Methyl 5&#8242;-(2-hydroxyphenyl)-4&#8242;,5&#8242;,6&#8242;,7&#8242;-tetrahydrospiro[2H-1-benzopyran-2,7&#8242;-1,2,4-triazolo[1,5-a]pyrimidine]-3-carboxylate
by: Jan Sv&#283;tl&#237;k, et al.
Published: (2011-01-01)

5-(4,4&#8242;&#8242;-Difluoro-5&#8242;-hydroxy-1,1&#8242;:3&#8242;,1&#8242;&#8242;-terphenyl-4&#8242;-yl)-3-(morpholin-4-ylmethyl)-1,3,4-oxadiazole-2(3H)-thione
by: Hoong-Kun Fun, et al.
Published: (2011-12-01)

1-(Phenylsulfonyl)benzo[1,2:2&#8242;,3&#8242;]thieno[5&#8242;,4&#8242;-b]carbazole
by: S. Thenmozhi, et al.
Published: (2010-04-01)

1&#8242;-Methyl-4&#8242;-(4-methylphenyl)dispiro[1-benzopyran-3(4H),3&#8242;-pyrrolidine-2&#8242;,3&#8242;&#8242;-indoline]-2,2&#8242;&#8242;-dione
by: D. Lakshmanan, et al.
Published: (2012-01-01)

Structure/Activity Analysis of TASK-3 Channel Antagonists Based on a 5,6,7,8 tetrahydropyrido[4,3-d]pyrimidine
by: David Ramírez, et al.
Published: (2019-05-01)

(2E)-1-(4,4&#8242;&#8242;-Difluoro-5&#8242;-methoxy-1,1&#8242;:3&#8242;,1&#8242;&#8242;-terphenyl-4&#8242;-yl)-3-(4-fluorophenyl)prop-2-en-1-one
by: Richard Betz, et al.
Published: (2011-11-01)

1&#8242;-Methyl-2,2&#8242;&#8242;-dioxoindoline-3-spiro-2&#8242;-pyrrolidine-3&#8242;-spiro-3&#8242;&#8242;-indoline-4&#8242;,4&#8242;-dicarbonitrile
by: P. Ramesh, et al.
Published: (2009-08-01)

2&#8242;,3,4,4&#8242;,5-Pentamethoxychalcone
by: Johannes H. van Tonder, et al.
Published: (2010-11-01)

5,6-Dimethoxy-4&#8242;,5&#8242;-diphenylindane-2-spiro-3&#8242;-pyrrolidine-2&#8242;-spiro-3&#8242;&#8242;-indoline-1,2&#8242;&#8242;-dione
by: Hoong-Kun Fun, et al.
Published: (2010-10-01)

2,2&#8242;,4,4&#8242;,6,6&#8242;-Hexamethylbiphenyl-3,3&#8242;,5,5&#8242;-tetrayltetramethylene tetraacetate
by: Tuoping Hu
Published: (2009-06-01)

5,5&#8242;,5&#8242;&#8242;-Triphenyl-2,2&#8242;,2&#8242;&#8242;-[2,4,6-trimethylbenzene-1,3,5-triyltris(methylidenesulfanediyl)]tris(1,3,4-oxadiazole)
by: Wei Wang, et al.
Published: (2010-11-01)

Cannot write session to /tmp/vufind_sessions/sess_m6v6d5amk6d1942i7jh9u9unkq