Effect of Poly(L-lysine) and Heparin Coatings on the Surface of Polyester-Based Particles on Prednisolone Release and Biocompatibility

Effect of Poly(L-lysine) and Heparin Coatings on the Surface of Polyester-Based Particles on Prednisolone Release and Biocompatibility

A plethora of micro- and nanoparticle types are currently investigated for advanced ocular treatment due to improved drug retention times, higher bioavailability and better biocompatibility. Yet, comparative studies of both physicochemical and toxicological performance of these novel drug delivery s...

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Bibliographic Details
Main Authors: Abdelrahman Mohamed, Viktor Korzhikov-Vlakh, Nan Zhang, André Said, Iuliia Pilipenko, Monika Schäfer-Korting, Christian Zoschke, Tatiana Tennikova
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pharmaceutics
Subjects:
poly(ε-caprolactone)
poly(L-lactide)
polymeric nanoparticle
alternative methods to animal testing
biocompatibility
eye diseases
Online Access:https://www.mdpi.com/1999-4923/13/6/801

Internet

https://www.mdpi.com/1999-4923/13/6/801

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