Organic anion transporter 2 transcript variant 1 shows broad ligand selectivity when expressed in multiple cell lines
Organic anion transporter 2 (OAT2) is likely important for renal and hepatic drug elimination. Three variants of the OAT2 peptide sequence have been described – OAT2 transcript variant 1 (OAT2-tv1), OAT2 transcript variant 2 (OAT2-tv2) and OAT2 transcript variant 3 (OAT2-tv3). Early studies helpin...
Main Authors: | Adam G Hotchkiss, Liam eBerrigan, Ryan M Pelis |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-10-01
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Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00216/full |
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