Organic anion transporter 2 transcript variant 1 shows broad ligand selectivity when expressed in multiple cell lines

Organic anion transporter 2 (OAT2) is likely important for renal and hepatic drug elimination. Three variants of the OAT2 peptide sequence have been described – OAT2 transcript variant 1 (OAT2-tv1), OAT2 transcript variant 2 (OAT2-tv2) and OAT2 transcript variant 3 (OAT2-tv3). Early studies helpin...

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Bibliographic Details
Main Authors: Adam G Hotchkiss, Liam eBerrigan, Ryan M Pelis
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00216/full

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