Histone deacetylase HDA-4-mediated epigenetic regulation in space-flown C. elegans

Abstract Epigenetic changes during long-term spaceflight are beginning to be studied by NASA’s twin astronauts and other model organisms. Here, we evaluate the epigenetic regulation of gene expression in space-flown C. elegans by comparing wild type and histone deacetylase (hda)-4 mutants. Expressio...

Full description

Bibliographic Details
Main Authors: Atsushi Higashitani, Toko Hashizume, Mai Takiura, Nahoko Higashitani, Mika Teranishi, Rika Oshima, Sachiko Yano, Kana Kuriyama, Akira Higashibata
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:npj Microgravity
Online Access:https://doi.org/10.1038/s41526-021-00163-7