Identifying Common Features in the Activation of Melanocortin-2 Receptors: Studies on the <i>Xenopus tropicalis</i> Melanocortin-2 Receptor

Identifying Common Features in the Activation of Melanocortin-2 Receptors: Studies on the <i>Xenopus tropicalis</i> Melanocortin-2 Receptor

The interaction between the pituitary hormone, adrenocorticotropin (ACTH), and melanocortin-2 receptor (MC2R) orthologs involves the H6 F7 R8 W9 and R/K15 K16 R17 R18 motifs in ACTH making contact with corresponding contact sites on MC2R. Earlier studies have localized the common HFRW binding site o...

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Bibliographic Details
Main Authors: Perry E. Davis, Emily C. Wilkinson, Robert M. Dores
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Xenopus tropicalis</i>
melanocortin-2 receptor
activation
Online Access:https://www.mdpi.com/1422-0067/20/17/4166

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