The FATZO mouse, a next generation model of type 2 diabetes, develops NAFLD and NASH when fed a Western diet supplemented with fructose

The FATZO mouse, a next generation model of type 2 diabetes, develops NAFLD and NASH when fed a Western diet supplemented with fructose

Abstract Background Metabolic disorders such as insulin resistance, obesity, and hyperglycemia are prominent risk factors for the development of non-alcoholic fatty liver disease (NAFLD)/steatohepatitis (NASH). Dietary rodent models employ high fat, high cholesterol, high fructose, methionine/cholin...

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Bibliographic Details
Main Authors: Gao Sun, Charles V. Jackson, Karen Zimmerman, Li-Kun Zhang, Courtney M. Finnearty, George E. Sandusky, Guodong Zhang, Richard G. Peterson, Yi-Xin (Jim) Wang
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Gastroenterology
Subjects:
Metabolic disease
Liver disease
NAFLD
NASH
FATZO mouse
Online Access:http://link.springer.com/article/10.1186/s12876-019-0958-4

Internet

http://link.springer.com/article/10.1186/s12876-019-0958-4

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