How Autophagy Shapes the Tumor Microenvironment in Ovarian Cancer

How Autophagy Shapes the Tumor Microenvironment in Ovarian Cancer

Ovarian cancer (OC) is characterized by a high mortality rate due to the late diagnosis and the elevated metastatic potential. Autophagy, a lysosomal-driven catabolic process, contributes to the macromolecular turnover, cell homeostasis, and survival, and as such, it represents a pathway targetable...

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Bibliographic Details
Main Authors: Alessandra Ferraresi, Carlo Girone, Andrea Esposito, Chiara Vidoni, Letizia Vallino, Eleonora Secomandi, Danny N. Dhanasekaran, Ciro Isidoro
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Oncology
Subjects:
cancer
cell metabolism
dormancy
cytokines
chemoresistance
autophagy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.599915/full

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