Systemic alendronate prevents resorption of necrotic bone during revascularization. A bone chamber study in rats

<p>Abstract</p> <p>Background</p> <p>Avascular necrosis of bone (osteonecrosis) can cause structural failure and subsequent deformation, leading to joint dysfunction and pain. Structural failure is the result of resorption of necrotic bone during revascularization, befo...

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Bibliographic Details
Main Authors: Aspenberg Per, Åstrand Jörgen
Format: Article
Language:English
Published: BMC 2002-08-01
Series:BMC Musculoskeletal Disorders
Online Access:http://www.biomedcentral.com/1471-2474/3/19