Practical uses for ecdysteroids in mammals including humans: An update
Ecdysteroids are widely used as inducers for gene-switch systems based on insect ecdysteroid receptors and genes of interest placed under the control of ecdysteroid-response elements. We review here these systems, which are currently mainly used in vitro with cultured cells in order to analyse the r...
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| Format: | Article |
| Language: | English |
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Oxford University Press
2003-03-01
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| Series: | Journal of Insect Science |
| Online Access: | http://www.insectscience.org/3.7/ |
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doaj-94a89b2f9cc04eeca263baf40f1548eb |
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Article |
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doaj-94a89b2f9cc04eeca263baf40f1548eb2020-11-24T21:32:40ZengOxford University PressJournal of Insect Science1536-24422003-03-0137Practical uses for ecdysteroids in mammals including humans: An updateR. LafontL. DinanEcdysteroids are widely used as inducers for gene-switch systems based on insect ecdysteroid receptors and genes of interest placed under the control of ecdysteroid-response elements. We review here these systems, which are currently mainly used in vitro with cultured cells in order to analyse the role of a wide array of genes, but which are expected to represent the basis for future gene therapy strategies. Such developments raise several questions, which are addressed in detail.http://www.insectscience.org/3.7/ |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
R. Lafont L. Dinan |
| spellingShingle |
R. Lafont L. Dinan Practical uses for ecdysteroids in mammals including humans: An update Journal of Insect Science |
| author_facet |
R. Lafont L. Dinan |
| author_sort |
R. Lafont |
| title |
Practical uses for ecdysteroids in mammals including humans: An update |
| title_short |
Practical uses for ecdysteroids in mammals including humans: An update |
| title_full |
Practical uses for ecdysteroids in mammals including humans: An update |
| title_fullStr |
Practical uses for ecdysteroids in mammals including humans: An update |
| title_full_unstemmed |
Practical uses for ecdysteroids in mammals including humans: An update |
| title_sort |
practical uses for ecdysteroids in mammals including humans: an update |
| publisher |
Oxford University Press |
| series |
Journal of Insect Science |
| issn |
1536-2442 |
| publishDate |
2003-03-01 |
| description |
Ecdysteroids are widely used as inducers for gene-switch systems based on insect ecdysteroid receptors and genes of interest placed under the control of ecdysteroid-response elements. We review here these systems, which are currently mainly used in vitro with cultured cells in order to analyse the role of a wide array of genes, but which are expected to represent the basis for future gene therapy strategies. Such developments raise several questions, which are addressed in detail. |
| url |
http://www.insectscience.org/3.7/ |
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AT rlafont practicalusesforecdysteroidsinmammalsincludinghumansanupdate AT ldinan practicalusesforecdysteroidsinmammalsincludinghumansanupdate |
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