Prostatic acid phosphatase is required for the antinociceptive effects of thiamine and benfotiamine.

Thiamine (Vitamin B1) is an essential vitamin that must be obtained from the diet for proper neurological function. At higher doses, thiamine and benfotiamine (S-benzoylthiamine O-monophosphate, BT)-a phosphorylated derivative of thiamine-have antinociceptive effects in animals and humans, although...

Full description

Bibliographic Details
Main Authors: Julie K Hurt, Jennifer L Coleman, Brendan J Fitzpatrick, Bonnie Taylor-Blake, Arlene S Bridges, Pirkko Vihko, Mark J Zylka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23119057/pdf/?tool=EBI