Recent Experiences and Advances in Contrast-Enhanced Subharmonic Ultrasound

Nonlinear contrast-enhanced ultrasound imaging schemes strive to suppress tissue signals in order to better visualize nonlinear signals from blood-pooling ultrasound contrast agents. Because tissue does not generate a subharmonic response (i.e., signal at half the transmit frequency), subharmonic im...

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Main Authors: John R. Eisenbrey, Anush Sridharan, Ji-Bin Liu, Flemming Forsberg
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/640397
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spelling doaj-94a30cc67b324741ab0d474cfb7a0d352020-11-25T01:00:19ZengHindawi LimitedBioMed Research International2314-61332314-61412015-01-01201510.1155/2015/640397640397Recent Experiences and Advances in Contrast-Enhanced Subharmonic UltrasoundJohn R. Eisenbrey0Anush Sridharan1Ji-Bin Liu2Flemming Forsberg3Department of Radiology, Thomas Jefferson University, 132 South 10th Street, Philadelphia, PA 19107, USADepartment of Radiology, Thomas Jefferson University, 132 South 10th Street, Philadelphia, PA 19107, USADepartment of Radiology, Thomas Jefferson University, 132 South 10th Street, Philadelphia, PA 19107, USADepartment of Radiology, Thomas Jefferson University, 132 South 10th Street, Philadelphia, PA 19107, USANonlinear contrast-enhanced ultrasound imaging schemes strive to suppress tissue signals in order to better visualize nonlinear signals from blood-pooling ultrasound contrast agents. Because tissue does not generate a subharmonic response (i.e., signal at half the transmit frequency), subharmonic imaging has been proposed as a method for isolating ultrasound microbubble signals while suppressing surrounding tissue signals. In this paper, we summarize recent advances in the use of subharmonic imaging in vivo. These advances include the implementation of subharmonic imaging on linear and curvilinear arrays, intravascular probes, and three-dimensional probes for breast, renal, liver, plaque, and tumor imaging.http://dx.doi.org/10.1155/2015/640397
collection DOAJ
language English
format Article
sources DOAJ
author John R. Eisenbrey
Anush Sridharan
Ji-Bin Liu
Flemming Forsberg
spellingShingle John R. Eisenbrey
Anush Sridharan
Ji-Bin Liu
Flemming Forsberg
Recent Experiences and Advances in Contrast-Enhanced Subharmonic Ultrasound
BioMed Research International
author_facet John R. Eisenbrey
Anush Sridharan
Ji-Bin Liu
Flemming Forsberg
author_sort John R. Eisenbrey
title Recent Experiences and Advances in Contrast-Enhanced Subharmonic Ultrasound
title_short Recent Experiences and Advances in Contrast-Enhanced Subharmonic Ultrasound
title_full Recent Experiences and Advances in Contrast-Enhanced Subharmonic Ultrasound
title_fullStr Recent Experiences and Advances in Contrast-Enhanced Subharmonic Ultrasound
title_full_unstemmed Recent Experiences and Advances in Contrast-Enhanced Subharmonic Ultrasound
title_sort recent experiences and advances in contrast-enhanced subharmonic ultrasound
publisher Hindawi Limited
series BioMed Research International
issn 2314-6133
2314-6141
publishDate 2015-01-01
description Nonlinear contrast-enhanced ultrasound imaging schemes strive to suppress tissue signals in order to better visualize nonlinear signals from blood-pooling ultrasound contrast agents. Because tissue does not generate a subharmonic response (i.e., signal at half the transmit frequency), subharmonic imaging has been proposed as a method for isolating ultrasound microbubble signals while suppressing surrounding tissue signals. In this paper, we summarize recent advances in the use of subharmonic imaging in vivo. These advances include the implementation of subharmonic imaging on linear and curvilinear arrays, intravascular probes, and three-dimensional probes for breast, renal, liver, plaque, and tumor imaging.
url http://dx.doi.org/10.1155/2015/640397
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