IFN-γ surmounts PD-L1/PD1 inhibition to CAR-T cell therapy by upregulating ICAM-1 on tumor cells

IFN-γ surmounts PD-L1/PD1 inhibition to CAR-T cell therapy by upregulating ICAM-1 on tumor cells

Bibliographic Details
Main Authors: E Dong, Xiao-zhu Yue, Lin Shui, Bin-rui Liu, Qi-qi Li, Yun Yang, Hui Luo, Wei Wang, Han-shuo Yang
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-020-00357-7
id doaj-9484a4d0369048318ad6f7e8695478fd
record_format Article
spelling doaj-9484a4d0369048318ad6f7e8695478fd2021-01-17T12:19:25ZengNature Publishing GroupSignal Transduction and Targeted Therapy2059-36352021-01-01611310.1038/s41392-020-00357-7IFN-γ surmounts PD-L1/PD1 inhibition to CAR-T cell therapy by upregulating ICAM-1 on tumor cellsE Dong0Xiao-zhu Yue1Lin Shui2Bin-rui Liu3Qi-qi Li4Yun Yang5Hui Luo6Wei Wang7Han-shuo Yang8State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for BiotherapyState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for BiotherapyState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for BiotherapyState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for BiotherapyState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for BiotherapyState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for BiotherapyState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for BiotherapyState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for BiotherapyState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapyhttps://doi.org/10.1038/s41392-020-00357-7
collection DOAJ
language English
format Article
sources DOAJ
author E Dong
Xiao-zhu Yue
Lin Shui
Bin-rui Liu
Qi-qi Li
Yun Yang
Hui Luo
Wei Wang
Han-shuo Yang
spellingShingle E Dong
Xiao-zhu Yue
Lin Shui
Bin-rui Liu
Qi-qi Li
Yun Yang
Hui Luo
Wei Wang
Han-shuo Yang
IFN-γ surmounts PD-L1/PD1 inhibition to CAR-T cell therapy by upregulating ICAM-1 on tumor cells
Signal Transduction and Targeted Therapy
author_facet E Dong
Xiao-zhu Yue
Lin Shui
Bin-rui Liu
Qi-qi Li
Yun Yang
Hui Luo
Wei Wang
Han-shuo Yang
author_sort E Dong
title IFN-γ surmounts PD-L1/PD1 inhibition to CAR-T cell therapy by upregulating ICAM-1 on tumor cells
title_short IFN-γ surmounts PD-L1/PD1 inhibition to CAR-T cell therapy by upregulating ICAM-1 on tumor cells
title_full IFN-γ surmounts PD-L1/PD1 inhibition to CAR-T cell therapy by upregulating ICAM-1 on tumor cells
title_fullStr IFN-γ surmounts PD-L1/PD1 inhibition to CAR-T cell therapy by upregulating ICAM-1 on tumor cells
title_full_unstemmed IFN-γ surmounts PD-L1/PD1 inhibition to CAR-T cell therapy by upregulating ICAM-1 on tumor cells
title_sort ifn-γ surmounts pd-l1/pd1 inhibition to car-t cell therapy by upregulating icam-1 on tumor cells
publisher Nature Publishing Group
series Signal Transduction and Targeted Therapy
issn 2059-3635
publishDate 2021-01-01
url https://doi.org/10.1038/s41392-020-00357-7
work_keys_str_mv AT edong ifngsurmountspdl1pd1inhibitiontocartcelltherapybyupregulatingicam1ontumorcells
AT xiaozhuyue ifngsurmountspdl1pd1inhibitiontocartcelltherapybyupregulatingicam1ontumorcells
AT linshui ifngsurmountspdl1pd1inhibitiontocartcelltherapybyupregulatingicam1ontumorcells
AT binruiliu ifngsurmountspdl1pd1inhibitiontocartcelltherapybyupregulatingicam1ontumorcells
AT qiqili ifngsurmountspdl1pd1inhibitiontocartcelltherapybyupregulatingicam1ontumorcells
AT yunyang ifngsurmountspdl1pd1inhibitiontocartcelltherapybyupregulatingicam1ontumorcells
AT huiluo ifngsurmountspdl1pd1inhibitiontocartcelltherapybyupregulatingicam1ontumorcells
AT weiwang ifngsurmountspdl1pd1inhibitiontocartcelltherapybyupregulatingicam1ontumorcells
AT hanshuoyang ifngsurmountspdl1pd1inhibitiontocartcelltherapybyupregulatingicam1ontumorcells
_version_ 1724335152011673600

Similar Items