Enhancement of tumour-specific immune responses in vivo by 'MHC loading-enhancer' (MLE).

Enhancement of tumour-specific immune responses in vivo by 'MHC loading-enhancer' (MLE).

BACKGROUND:Class II MHC molecules (MHC II) are cell surface receptors displaying short protein fragments for the surveillance by CD4+ T cells. Antigens therefore have to be loaded onto this receptor in order to induce productive immune responses. On the cell surface, most MHC II molecules are either...

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Bibliographic Details
Main Authors: Katharina Dickhaut, Sabine Hoepner, Jamina Eckhard, Karl-Heinz Wiesmueller, Luise Schindler, Guenther Jung, Kirsten Falk, Olaf Roetzschke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2735034?pdf=render

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http://europepmc.org/articles/PMC2735034?pdf=render

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