Both lethal and edema toxins of Bacillus anthracis disrupt the human dendritic cell chemokine network.

Both lethal and edema toxins of Bacillus anthracis disrupt the human dendritic cell chemokine network.

Bacillus anthracis, the agent of anthrax, produces two main virulence factors: a capsule and two toxins. Both lethal toxin (LT) and edema toxin (ET) paralyze the immune defense system. Here, we analyze the effects of LT and ET on the capacity of human monocyte-derived dendritic cells (MoDC) to produ...

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Bibliographic Details
Main Authors: Aurélie Cleret-Buhot, Jacques Mathieu, Jean-Nicolas Tournier, Anne Quesnel-Hellmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3427382?pdf=render

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