Exploration of Piperidinols as Potential Antitubercular Agents

Exploration of Piperidinols as Potential Antitubercular Agents

Novel drugs to treat tuberculosis are required and the identification of potential targets is important. Piperidinols have been identified as potential antimycobacterial agents (MIC < 5 μg/mL), which also inhibit mycobacterial arylamine N-acetyltransferase (NAT), an enzyme essential for mycob...

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Bibliographic Details
Main Authors: Areej Abuhammad, Elizabeth Fullam, Sanjib Bhakta, Angela J. Russell, Garrett M. Morris, Paul W. Finn, Edith Sim
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:Molecules
Subjects:
tuberculosis
covalent inhibitors
piperidinols
arylamine N-acetyltransferase
Online Access:http://www.mdpi.com/1420-3049/19/10/16274

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