Methylation Pattern of the SOCS3 and IL6R Promoters in Rheumatoid Arthritis

Methylation Pattern of the SOCS3 and IL6R Promoters in Rheumatoid Arthritis

Interleukin-6 (IL-6) plays an essential function in the development of rheumatoid arthritis (RA), mainly through its proinflammatory effect, which may lead to joint destruction. The genes encoding IL-6 receptor (IL6R) and suppressor of cytokine signaling 3 (SOCS3) play a key role in the IL-6 signali...

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Bibliographic Details
Main Authors:	Marek Cieśla, Bogdan Kolarz, Maria Majdan, Dorota Darmochwał-Kolarz
Format:	Article
Language:	English
Published:	Hindawi Limited 2020-01-01
Series:	International Journal of Inflammation
Online Access:	http://dx.doi.org/10.1155/2020/8394659

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