Initial Method for Characterization of Tympanic Membrane Drug Permeability in Human Temporal Bones In Situ

Background and Introduction: Acute otitis media is the most common reason for a visit to the pediatrician, often requiring systemic administration of oral antibiotics. Local drug therapy applied to the middle ear could avoid side effects associated with systemic antibiotic administration, however in...

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Bibliographic Details
Main Authors: Samuel Early, Rong Yang, Xiyu Li, Zipei Zhang, Jens C. van der Valk, Xiaojie Ma, Daniel S. Kohane, Konstantina M. Stankovic
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.580392/full