Cortical Glutamate and GABA Changes During Early Abstinence in Alcohol Dependence and Their Associations With Benzodiazepine Medication

Cortical Glutamate and GABA Changes During Early Abstinence in Alcohol Dependence and Their Associations With Benzodiazepine Medication

In this report, we present cross-sectional and longitudinal findings from single-voxel MEGA-PRESS MRS of GABA as well as Glu, and Glu + glutamine (Glx) concentrations in the ACC of treatment-seeking alcohol-dependent patients (ADPs) during detoxification (first 2 weeks of abstinence). The focus of t...

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Bibliographic Details
Main Authors: Guoying Wang, Wolfgang Weber-Fahr, Ulrich Frischknecht, Derik Hermann, Falk Kiefer, Gabriele Ende, Markus Sack
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Psychiatry
Subjects:
alcohol dependence
glutamate
GABA
benzodiazepine
withdrawal
N-acetylaspartate
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2021.656468/full

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