Peptide KSL-W-Loaded Mucoadhesive Liquid Crystalline Vehicle as an Alternative Treatment for Multispecies Oral Biofilm

Peptide KSL-W-Loaded Mucoadhesive Liquid Crystalline Vehicle as an Alternative Treatment for Multispecies Oral Biofilm

Decapeptide KSL-W shows antibacterial activities and can be used in the oral cavity, however, it is easily degraded in aqueous solution and eliminated. Therefore, we aimed to develop liquid crystalline systems (F1 and F2) for KSL-W buccal administration to treat multispecies oral biofilms. The syste...

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Bibliographic Details
Main Authors: Jéssica Bernegossi, Giovana Maria Fioramonti Calixto, Paulo Ricardo da Silva Sanches, Carla Raquel Fontana, Eduardo Maffud Cilli, Saulo Santesso Garrido, Marlus Chorilli
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Molecules
Subjects:
liquid crystalline systems
oral cavity
biofilm
KSL-W
antimicrobial peptide
Online Access:http://www.mdpi.com/1420-3049/21/1/37

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