Analysis and Biological Evaluation of Arisaema Amuremse Maxim Essential Oil

• Main Authors: Li Guiying, Jiang Yueyao, Li Yingjun, He Tong, Wang Ying, Ji Tianyi, Zhai Wanchen, Zhao Lichun, Zhou Xiaoping
• Format: Article
• Language: English
• Published: De Gruyter 2019-09-01
• Series: Open Chemistry
• Subjects: arisaema; amuremse; maxim essential oil; mtt
• Online Access: http://www.degruyter.com/view/j/chem.2019.17.issue-1/chem-2019-0054/chem-2019-0054.xml?format=INT

The chemical composition and antitumor activity of essential oil were compared for four parts of the Arisaema Amuremse Maxim. Chemical constituent of essential oil in every parts of Arisaema Amuremse Maxim was identified by GC-MS analysis systematically. Arisaema Amuremse Maxim had 114 kinds of essential oils. Tubers, petioles, leaves, and fruits were identified 53, 48, 5 and 21 species essential oil, respectively. The antiproliferative activity against Hep2, HCT-116, A549, SW480, HepG2 cell lines had been investigated by MTT assay. The essential oil of tubers, petioles, leaves and fruits all had strong antiproliferative activity. The IC 50 was 19.60μg·mL-1, 17.60μg·mL-1, 23.80μg·mL-1, and 30.23μg·mL-1, respectively. Among them, the essential oil of tubers and petioles had stronger antitumor activity. The essential oil of tubers, petioles, leaves and fruits had strong antiproliferative activity. This study was of great significance to increase the medicinal parts of Arisaema Amuremse Maxim.