IL-25–induced shifts in macrophage polarization promote development of beige fat and improve metabolic homeostasis in mice

Beige fat dissipates energy and functions as a defense against cold and obesity, but the mechanism for its development is unclear. We found that interleukin (IL)-25 signaling through its cognate receptor, IL-17 receptor B (IL-17RB), increased in adipose tissue after cold exposure and β3-adrenoceptor...

Full description

Bibliographic Details
Main Authors: Lingyi Li, Lei Ma, Zewei Zhao, Shiya Luo, Baoyong Gong, Jin Li, Juan Feng, Hui Zhang, Weiwei Qi, Ti Zhou, Xia Yang, Guoquan Gao, Zhonghan Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-08-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341513/?tool=EBI