Evaluating Oxygen Tensions Related to Bone Marrow and Matrix for MSC Differentiation in 2D and 3D Biomimetic Lamellar Scaffolds

Evaluating Oxygen Tensions Related to Bone Marrow and Matrix for MSC Differentiation in 2D and 3D Biomimetic Lamellar Scaffolds

The physiological O<sub>2</sub> microenvironment of mesenchymal stem cells (MSCs) and osteoblasts and the dimensionality of a substrate are known to be important in regulating cell phenotype and function. By providing the physiologically normoxic environments of bone marrow (5%) and matr...

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Bibliographic Details
Main Authors: Esen Sayin, Erkan Türker Baran, Ahmed Elsheikh, Vivek Mudera, Umber Cheema, Vasif Hasirci
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
oxygen tension
2D vs. 3D
mesenchymal stem cell
osteogenesis
bone tissue engineering
Online Access:https://www.mdpi.com/1422-0067/22/8/4010

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