Circulating type-1 anti-tumor CD4+ T cells are preferentially pro-apoptotic in cancer patients
Melanoma patients frequently exhibit a deficiency in Type-1 (but not Type-2 or regulatory) CD4+ T cell responses against tumor-associated antigens (TAA), which may limit protection against cancer progression or responsiveness to immunotherapy in these individuals. Since such deficiency was acutely e...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2014-09-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00266/full |