Mechanisms of therapeutic resistance in cancer (stem) cells with emphasis on thyroid cancer cells.

Tissue invasion, metastasis and therapeutic resistance to anti-cancer treatments are common and main causes of death in cancer patients. Tumor cells mount complex and still poorly understood molecular defense mechanisms to counteract and evade oxygen deprivation, nutritional restrictions as well as...

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Bibliographic Details
Main Authors: Sabine eHombach-Klonisch, Suchitra eNatarajan, Thatchawan eThanasupawat, Manoj Reddy Medapati, Alok ePathak, Saeid eGhavami, Thomas eKlonisch
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00037/full