The Role of Smoothened in Cancer

The Role of Smoothened in Cancer

Smoothened (SMO) belongs to the Hedgehog (HH) signaling pathway, which regulates cell growth, migration, invasion and stem cells in cancer. The HH signaling pathway includes both canonical and noncanonical pathways. The canonical HH pathway functions through major HH molecules such as HH ligands, PT...

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Bibliographic Details
Main Authors:	Kuo-Shyang Jeng, I-Shyan Sheen, Chuen-Miin Leu, Ping-Hui Tseng, Chiung-Fang Chang
Format:	Article
Language:	English
Published:	MDPI AG 2020-09-01
Series:	International Journal of Molecular Sciences
Subjects:	Smoothened Hedgehog signaling pathway cancer stem cells
Online Access:	https://www.mdpi.com/1422-0067/21/18/6863

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