Corneal endothelial expansion promoted by human bone marrow mesenchymal stem cell-derived conditioned medium.

Healthy corneal endothelium is essential for maintaining corneal clarity, as the damage of corneal endothelial cells and loss of cell count causes severe visual impairment. Corneal transplantation is currently the only therapy for severe corneal disorders. The greatly limited proliferative ability o...

Full description

Bibliographic Details
Main Authors: Makiko Nakahara, Naoki Okumura, EunDuck P Kay, Michio Hagiya, Kiwamu Imagawa, Yuuki Hosoda, Shigeru Kinoshita, Noriko Koizumi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3720876?pdf=render