The use of very high-doses of baclofen for the treatment of alcohol-dependence: a case series.

Baclofen, particularly high-dose baclofen, has recently emerged as a treatment of major interest for alcohol-dependence. However, baclofen has many potentially dangerous side effects, and the maximal dose of baclofen that may be used is a matter of discussion. Here, the author analyses the medical c...

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Main Author: Renaud ede Beaurepaire
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpsyt.2014.00143/full
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spelling doaj-93ff6ec7b2f0421588df120641930be52020-11-24T23:03:46ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402014-10-01510.3389/fpsyt.2014.00143111504The use of very high-doses of baclofen for the treatment of alcohol-dependence: a case series.Renaud ede Beaurepaire0GHPGBaclofen, particularly high-dose baclofen, has recently emerged as a treatment of major interest for alcohol-dependence. However, baclofen has many potentially dangerous side effects, and the maximal dose of baclofen that may be used is a matter of discussion. Here, the author analyses the medical charts of the last 100 patients seen in his clinic, 17 of whom have been taking a very high dose of baclofen, that is to say, more than 300mg per day. The analysis of the charts shows that the very high doses baclofen were justified in almost all the cases. Side effects are analyzed.http://journal.frontiersin.org/Journal/10.3389/fpsyt.2014.00143/fullAlcoholismAddictionTreatmentAbstinenceSide-effect
collection DOAJ
language English
format Article
sources DOAJ
author Renaud ede Beaurepaire
spellingShingle Renaud ede Beaurepaire
The use of very high-doses of baclofen for the treatment of alcohol-dependence: a case series.
Frontiers in Psychiatry
Alcoholism
Addiction
Treatment
Abstinence
Side-effect
author_facet Renaud ede Beaurepaire
author_sort Renaud ede Beaurepaire
title The use of very high-doses of baclofen for the treatment of alcohol-dependence: a case series.
title_short The use of very high-doses of baclofen for the treatment of alcohol-dependence: a case series.
title_full The use of very high-doses of baclofen for the treatment of alcohol-dependence: a case series.
title_fullStr The use of very high-doses of baclofen for the treatment of alcohol-dependence: a case series.
title_full_unstemmed The use of very high-doses of baclofen for the treatment of alcohol-dependence: a case series.
title_sort use of very high-doses of baclofen for the treatment of alcohol-dependence: a case series.
publisher Frontiers Media S.A.
series Frontiers in Psychiatry
issn 1664-0640
publishDate 2014-10-01
description Baclofen, particularly high-dose baclofen, has recently emerged as a treatment of major interest for alcohol-dependence. However, baclofen has many potentially dangerous side effects, and the maximal dose of baclofen that may be used is a matter of discussion. Here, the author analyses the medical charts of the last 100 patients seen in his clinic, 17 of whom have been taking a very high dose of baclofen, that is to say, more than 300mg per day. The analysis of the charts shows that the very high doses baclofen were justified in almost all the cases. Side effects are analyzed.
topic Alcoholism
Addiction
Treatment
Abstinence
Side-effect
url http://journal.frontiersin.org/Journal/10.3389/fpsyt.2014.00143/full
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