Evidence for oxidative stress and defective antioxidant response in guinea pigs with tuberculosis.

The development of granulomatous inflammation with caseous necrosis is an important but poorly understood manifestation of tuberculosis in humans and some animal models. In this study we measured the byproducts of oxidative stress in granulomatous lesions as well as the systemic antioxidant capacity...

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Bibliographic Details
Main Authors: Gopinath S Palanisamy, Natalie M Kirk, David F Ackart, Crystal A Shanley, Ian M Orme, Randall J Basaraba
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3196542?pdf=render