Unravelling the interplay of sphingolipids and TGF-β signaling in the human corneal stroma.

Unravelling the interplay of sphingolipids and TGF-β signaling in the human corneal stroma.

To delineate the role of Sphingolipids (SPLs) in the human cornea and their cross-talks with transforming growth factor beta (TGF-β) in order to develop novel, non-invasive therapies.Human corneal fibroblasts (HCFs) were harvested from healthy donors, stimulated with Vitamin C to promote extracellul...

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Bibliographic Details
Main Authors: Sarah E Nicholas, Tyler G Rowsey, Shrestha Priyadarsini, Nawajes A Mandal, Dimitrios Karamichos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5555661?pdf=render

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