Disulfiram efficacy in the treatment of alcohol dependence: a meta-analysis.

BACKGROUND: Despite its success with compliant or supervised patients, disulfiram has been a controversial medication in the treatment of alcoholism. Often, study designs did not recognize a pivotal factor in disulfiram research, the importance of an open-label design. Our objectives are: (1) to ana...

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Bibliographic Details
Main Authors: Marilyn D Skinner, Pierre Lahmek, Héloïse Pham, Henri-Jean Aubin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3919718?pdf=render